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This cotransporter mediates sodium and chloride reabsorption in the distal convoluted tubule. Complete information for fas gene (protein coding), fas cell surface death receptor, including Lrrk2 (leucine rich repeat kinase 2) is a protein coding gene

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Diseases associated with lrrk2 include parkinson disease 8, autosomal dominant and parkinson's disease. Complete information for yap1 gene (protein coding), yes1 associated transcriptional regulator, including Function, proteins, disorders, pathways, orthologs, and expression.

The protein encoded by this gene localizes to both the cytoplasm and the nucleus

Within the nucleus, the protein localizes to subnuclear bodies called gems which are found near coiled bodies containing high concentrations of small ribonucleoproteins (snrnps). The encoded protein is believed to be an integral membrane protein involved in small molecule transport, specifically tyrosine, which is a precursor to melanin synthesis.