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Entries removed from unreviewed uniprotkb/trembl will remain accessible in the uniparc sequence archive Bifunctional enzyme that catalyzes the last two steps of purine biosynthesis (pubmed:11948179, pubmed:14756554). Please read our help page, view affected entries and proteomes, or contact us with any questions

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Aicar causes profound mental retardation, epilepsy, dysmorphic features and congenital blindness. Premade recombinant proteins and custom services are both available. Bifunctional purine biosynthesis protein atic protein family protein sequence protein function catalytic activity

Publications download data as a json file expand annotation collapse annotation

Atic together with prkaa2/ampk2 and hacd3/ptplad1 is proposed to be part of a signaling network regulating insr autophosphorylation and endocytosis (pubmed:25687571).